TRMU
Mitochondrial tRNA-specific 2-thiouridylase 1
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.9 | ||
tissue sample | 0.68 | ||
small molecule perturbation | 0.64 | ||
virus perturbation | 0.64 | ||
cell type or tissue | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | tRNA modification in the mitochondrion | ||||
Reactome | tRNA processing | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
tRNA modification in the mitochondrion | ||||
tRNA processing | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
testosterone measurement | 3 | 3 | 6 | 89.8 | |||||
triglyceride measurement | 2 | 2 | 2 | 55.8 | |||||
alkaline phosphatase measurement | 1 | 1 | 1 | 52 | |||||
heel bone mineral density | 1 | 1 | 1 | 33.1 | |||||
total cholesterol measurement | 1 | 1 | 1 | 24.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
testosterone measurement | 6 | 89.8 | |||||
triglyceride measurement | 2 | 55.8 | |||||
alkaline phosphatase measurement | 1 | 52 | |||||
heel bone mineral density | 1 | 33.1 | |||||
total cholesterol measurement | 1 | 24.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | VGNC:12934 | 458914 | |||||
Macaque | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | 714268 | ||||||
Mouse | MGI:1919276 | 72026 | ||||||
Rat | RGD:1311229 | 362976 | ||||||
Dog | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | VGNC:47861 | 481204 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | |||||
Macaque | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | |||||
Mouse | ||||||
Rat | ||||||
Dog | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | |||||
PMID | Year | Title |
---|