Protein Classes
Protein Summary
May act as a chaperone. The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus. [provided by RefSeq, Oct 2008]
- ENST00000370110
- ENSP00000359128
- ENSG00000107833
- PORMIN
- TMEM123
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.77 | ||
small molecule perturbation | 0.75 | ||
drug perturbation | 0.71 | ||
PubMedID | 0.69 | ||
tissue sample | 0.68 | ||
Related Tools
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.61 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 113 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.61 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 113 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | nucleophosmin/nucleoplasmin 3 | VGNC:5583 | 450690 | |||||
Macaque | nucleophosmin/nucleoplasmin 3 | 712300 | ||||||
Mouse | MGI:894653 | 18150 | ||||||
Rat | RGD:1565542 | 502389 | ||||||
Dog | nucleophosmin/nucleoplasmin 3 | VGNC:43923 | 477801 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | nucleophosmin/nucleoplasmin 3 | |||||
Macaque | nucleophosmin/nucleoplasmin 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | nucleophosmin/nucleoplasmin 3 | |||||
Gene Ontology Terms (11)
Functions (3)
Components (5)
Processes (3)
Items per page:
10
1 – 3 of 3
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (39)
1 – 10 of 39
NPM1
Novelty: 0.0005485
p_int: 0.98504155
p_ni: 0.014957366
p_wrong: 0.000001083
Score: 0.741
Data Source: BioPlex,STRINGDB
NPM2
Novelty: 0.03674672
p_int: 0.984036617
p_ni: 0.015566099
p_wrong: 0.000397284
Score: 0.993
Data Source: BioPlex,STRINGDB
FKBP15
Novelty: 0.0570695
Score: 0.848
Data Source: STRINGDB
EEF1D
Novelty: 0.02480745
Score: 0.689
Data Source: STRINGDB
DUT
Family: Enzyme
Novelty: 0.0026993
Score: 0.686
Data Source: STRINGDB
H2AFZ
Novelty: 0.00222512
Score: 0.662
Data Source: STRINGDB
H2AFV
Novelty: 0.03561635
Score: 0.645
Data Source: STRINGDB
TRIM55
Novelty: 0.06290418
Score: 0.626
Data Source: STRINGDB
CHD1
Family: Epigenetic
Novelty: 0.00498132
Score: 0.625
Data Source: STRINGDB
FGF8
Novelty: 0.00155113
Score: 0.615
Data Source: STRINGDB
Publication Statistics
PubMed Score 8.61
PubMed score by year
PubTator Score 6.64
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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