NR1I2
Nuclear receptor subfamily 1 group I member 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
chemical | 1 | ||
co-expressed gene | 1 | ||
molecular function | 0.97 | ||
biological term | 0.8 | ||
biological process | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Nuclear Receptor transcription pathway | ||||
Reactome | Post-translational protein modification | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Metabolism of proteins | ||||
Nuclear Receptor transcription pathway | ||||
Post-translational protein modification | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 4 | 2 | 4 | 74.1 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 72.9 | |||||
low density lipoprotein cholesterol measurement | 1 | 1 | 1 | 52.7 | |||||
lymphocyte percentage of leukocytes | 1 | 1 | 1 | 50.6 | |||||
total cholesterol measurement | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 4 | 74.1 | |||||
apolipoprotein A 1 measurement | 1 | 72.9 | |||||
low density lipoprotein cholesterol measurement | 1 | 52.7 | |||||
lymphocyte percentage of leukocytes | 1 | 50.6 | |||||
total cholesterol measurement | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | nuclear receptor subfamily 1 group I member 2 | VGNC:7079 | 745458 | |||||
Macaque | nuclear receptor subfamily 1 group I member 2 | 574226 | ||||||
Mouse | MGI:1337040 | 18171 | ||||||
Rat | RGD:69057 | 84385 | ||||||
Dog | nuclear receptor subfamily 1 group I member 2 | VGNC:53079 | 403482 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | nuclear receptor subfamily 1 group I member 2 | |||||
Macaque | nuclear receptor subfamily 1 group I member 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | nuclear receptor subfamily 1 group I member 2 | |||||
PMID | Year | Title |
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