Protein Summary
Plays a role in the toxic effects of organotins (PubMed:15269288). Plays a role in endosomal maturation (PubMed:27015288).
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 225.56 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 8 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 225.56 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 8 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id | Ligand | Method | Resolution (Ã…) | M.W. (kDa) | Pub Year | Title |
---|
PDB Structure Id | M.W. | Resolution | Pub Year |
---|
Gene Ontology Terms (5)
Functions (1)
Components (3)
Processes (1)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | CAFA | |||
Protein-Protein Interactions (34)
1 – 10 of 34
MTDH
Novelty: 0.00211478
p_int: 0.999972217
p_ni: 0.000027783
Score: 0.309
Data Source: BioPlex,STRINGDB
TMX1
Novelty: 0.01558923
p_int: 0.998035127
p_ni: 0.001964873
Score: 0.196
Data Source: BioPlex,STRINGDB
TES
Novelty: 0.00112939
p_int: 0.997352366
p_ni: 0.002645344
p_wrong: 0.00000229
Score: 0.243
Data Source: BioPlex,STRINGDB
C1orf131
p_int: 0.944091511
p_ni: 0.048354637
p_wrong: 0.007553852
Score: 0.282
Data Source: BioPlex,STRINGDB
FST
Novelty: 0.00081807
Score: 0.785
Data Source: STRINGDB
SPIN4
Novelty: 0.21428571
Score: 0.733
Data Source: STRINGDB
TXNDC11
Novelty: 0.10709732
Score: 0.681
Data Source: STRINGDB
VIPR1
Family: GPCR
Novelty: 0.00222991
Score: 0.652
Data Source: STRINGDB
ADAMTS3
Family: Enzyme
Novelty: 0.00834011
Score: 0.646
Data Source: STRINGDB
YWHAZ
Novelty: 0.00235606
Score: 0.621
Data Source: STRINGDB
Publication Statistics
PubMed Score 225.56
PubMed score by year
PubTator Score 17.03
PubTator score by year
Amino Acid Sequence
Residue Counts
Sequence
MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGP
1-70
CVERKAKLMTPNGPEVHG
70-88
MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTPNGPEVHG
Find similar targets by: