Protein Classes
Protein Summary
Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]
- ENST00000207870
- ENSP00000207870
- ENSG00000093217
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.9 | ||
cell type or tissue | 0.79 | ||
tissue sample | 0.7 | ||
disease perturbation | 0.68 | ||
transcription factor perturbation | 0.68 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 114.72 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 79 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 114.72 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 79 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Data Bank (4)
1 – 4 of 4
PDB Structure Id | Ligand | Method | Resolution (Å) | M.W. (kDa) | Pub Year | Title |
|---|
PDB Structure Id | M.W. | Resolution | Pub Year |
|---|
Pathways (5)
Reactome (3)
KEGG (2)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 3 of 3
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Formation of xylulose-5-phosphate | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of carbohydrates | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Formation of xylulose-5-phosphate | ||||
Metabolism | ||||
Metabolism of carbohydrates | ||||
Gene Ontology Terms (11)
Functions (2)
Components (2)
Processes (7)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Protein-Protein Interactions (92)
1 – 10 of 92
RPE
Family: Enzyme
Novelty: 0.00825452
Score: 0.983
Data Source: STRINGDB
RPEL1
Family: Enzyme
Novelty: 0.67708333
Score: 0.965
Data Source: STRINGDB
SLC22A14
Family: Transporter
Novelty: 0.35477513
Score: 0.931
Data Source: STRINGDB
TALDO1
Family: Enzyme
Novelty: 0.00254889
Score: 0.928
Data Source: STRINGDB
SLC22A13
Family: Transporter
Novelty: 0.05026745
Score: 0.911
Data Source: STRINGDB
XDH
Family: Enzyme
Novelty: 0.00097175
Score: 0.875
Data Source: STRINGDB
SORD
Family: Enzyme
Novelty: 0.00508278
Score: 0.858
Data Source: STRINGDB
TKT
Family: Enzyme
Novelty: 0.0027011
Score: 0.809
Data Source: STRINGDB
OXSR1
Family: Kinase
Novelty: 0.22453889
Score: 0.8
Data Source: STRINGDB
AKR1B1
Family: Enzyme
Novelty: 0.00050572
Score: 0.784
Data Source: STRINGDB
Publication Statistics
PubMed Score 114.72
PubMed score by year
PubTator Score 12.46
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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