RNF40
E3 ubiquitin-protein ligase BRE1B
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.94 | ||
disease perturbation | 0.83 | ||
biological process | 0.73 | ||
microRNA | 0.67 | ||
tissue sample | 0.63 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | E3 ubiquitin ligases ubiquitinate target proteins | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Protein ubiquitination | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
E3 ubiquitin ligases ubiquitinate target proteins | ||||
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Protein ubiquitination | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 1 | 1 | 1 | 71.3 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 54.4 | |||||
HbA1c measurement | 1 | 1 | 1 | 52 | |||||
testosterone measurement | 2 | 2 | 2 | 46.5 | |||||
HMG CoA reductase inhibitor use measurement | 1 | 1 | 1 | 33.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 1 | 71.3 | |||||
comparative body size at age 10, self-reported | 1 | 54.4 | |||||
HbA1c measurement | 1 | 52 | |||||
testosterone measurement | 2 | 46.5 | |||||
HMG CoA reductase inhibitor use measurement | 1 | 33.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ring finger protein 40 | VGNC:9101 | 454054 | |||||
Macaque | ring finger protein 40 | 713148 | ||||||
Mouse | MGI:2142048 | 233900 | ||||||
Rat | RGD:628638 | 266712 | ||||||
Dog | ring finger protein 40 | VGNC:45669 | 489913 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ring finger protein 40 | |||||
Macaque | ring finger protein 40 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ring finger protein 40 | |||||
PMID | Year | Title |
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