SRGAP2
SLIT-ROBO Rho GTPase-activating protein 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.95 | ||
microRNA | 0.93 | ||
transcription factor perturbation | 0.84 | ||
cell line | 0.74 | ||
protein domain | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | Inactivation of CDC42 and RAC1 | ||||
Reactome | RHO GTPase Effectors | ||||
Reactome | RHO GTPases Activate Formins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Developmental Biology | ||||
Inactivation of CDC42 and RAC1 | ||||
RHO GTPase Effectors | ||||
RHO GTPases Activate Formins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 1 | 3 | 78.3 | |||||
3 | 3 | 2 | 1 | 64.3 | |||||
serum non-albumin protein measurement | 1 | 1 | 1 | 57.3 | |||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 54.4 | |||||
eosinophil count | 1 | 1 | 1 | 46.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 78.3 | |||||
2 | 1 | 64.3 | |||||
serum non-albumin protein measurement | 1 | 57.3 | |||||
eosinophil percentage of leukocytes | 1 | 54.4 | |||||
eosinophil count | 1 | 46.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | SLIT-ROBO Rho GTPase activating protein 2 | 695724 | ||||||
Mouse | MGI:109605 | 14270 | ||||||
Rat | RGD:1566016 | 360840 | ||||||
Dog | SLIT-ROBO Rho GTPase activating protein 2 | 478949 | ||||||
Horse | SLIT-ROBO Rho GTPase activating protein 2 | 100050923 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | SLIT-ROBO Rho GTPase activating protein 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | SLIT-ROBO Rho GTPase activating protein 2 | |||||
Horse | SLIT-ROBO Rho GTPase activating protein 2 | |||||
PMID | Year | Title |
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