Protein Classes
Protein Summary
May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE).
- ENST00000374496
- ENSP00000363620
- ENSG00000112514
- ENST00000374500
- ENSP00000363624
- ENST00000435267
- ENSP00000391509
- ENSG00000226492
- ENST00000440279
- ENSP00000403268
- ENST00000440930
- ENSP00000400114
- ENST00000487148
- ENSP00000432744
- ENST00000488034
- ENSP00000417544
- ENST00000607266
- ENSP00000475963
- ENST00000611509
- ENSP00000480360
- ACHAP
- C6orf82
- ACHAP
- C6orf82
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.99 | ||
disease perturbation | 0.9 | ||
transcription factor binding site profile | 0.84 | ||
transcription factor perturbation | 0.8 | ||
transcription factor | 0.77 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 46.58 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 164 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 46.58 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 164 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id | Ligand | Method | Resolution (Ã…) | M.W. (kDa) | Pub Year | Title |
---|
PDB Structure Id | M.W. | Resolution | Pub Year |
---|
Gene Ontology Terms (6)
Functions (2)
Components (2)
Processes (2)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (46)
1 – 10 of 46
UPP1
Family: Enzyme
Novelty: 0.01749136
p_int: 0.999999993
p_ni: 7e-9
p_wrong: 1e-9
Score: 0.297
Data Source: BioPlex,STRINGDB
PRKAA1
Family: Kinase
Novelty: 0.01012358
p_int: 0.998614332
p_ni: 0.001385668
Score: 0.696
Data Source: BioPlex,STRINGDB
FBLIM1
Novelty: 0.04280121
p_int: 0.998036292
p_ni: 0.001963708
Score: 0.252
Data Source: BioPlex,STRINGDB
CLTCL1
Novelty: 0.05165674
p_int: 0.997784224
p_ni: 0.002215776
Data Source: BioPlex
UBB
Novelty: 0.00895161
p_int: 0.995864567
p_ni: 0.004135433
Score: 0.172
Data Source: BioPlex,STRINGDB
PRKAB1
Family: Kinase
Novelty: 0.027886
p_int: 0.991844952
p_ni: 0.008153308
p_wrong: 0.000001739
Score: 0.56
Data Source: BioPlex,STRINGDB
GID4
Novelty: 0.10469899
p_int: 0.981481436
p_ni: 0.018518564
Data Source: BioPlex
ARMC8
Novelty: 0.08450354
p_int: 0.978821154
p_ni: 0.021178846
Data Source: BioPlex
ZER1
Novelty: 0.05686147
p_int: 0.976720146
p_ni: 0.023279854
Score: 0.173
Data Source: BioPlex,STRINGDB
PRKAG1
Family: Kinase
Novelty: 0.1139086
p_int: 0.953873813
p_ni: 0.046126187
Score: 0.765
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score 46.58
PubMed score by year
PubTator Score 11.82
PubTator score by year
Amino Acid Sequence
Residue Counts
Sequence
MSGGRAPAVLLGGVASLLLSFVWMPALLPVASRLLLLPRVLLTMASGSPPTQPSPASDSGSGYVPGSVSA
1-70
AFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSV
70-140
HPYEVAEVIALPVEQGNFPYLQWVRQVTESVSDSITVLP
140-179
MSGGRAPAVLLGGVASLLLSFVWMPALLPVASRLLLLPRVLLTMASGSPPTQPSPASDSGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIALPVEQGNFPYLQWVRQVTESVSDSITVLP
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