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Tbio
CUTA
Protein CutA

Protein Summary
Description
May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374496
  • ENSP00000363620
  • ENSG00000112514
  • ENST00000374500
  • ENSP00000363624
  • ENST00000435267
  • ENSP00000391509
  • ENSG00000226492
  • ENST00000440279
  • ENSP00000403268
  • ENST00000440930
  • ENSP00000400114
  • ENST00000487148
  • ENSP00000432744
  • ENST00000488034
  • ENSP00000417544
  • ENST00000607266
  • ENSP00000475963
  • ENST00000611509
  • ENSP00000480360

Symbol
  • ACHAP
  • C6orf82
  • ACHAP
  • C6orf82
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.99
disease perturbation
0.9
transcription factor binding site profile
0.84
transcription factor perturbation
0.8
transcription factor
0.77


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.05   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.05   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
UPP1
Tchem
Family:  Enzyme
Novelty:  0.01384975
p_int:  0.999999993
p_ni:  7e-9
p_wrong:  1e-9
Score:  0.297
Data Source:  BioPlex,STRINGDB
PRKAA1
Tclin
Family:  Kinase
Novelty:  0.01205826
p_int:  0.998614332
p_ni:  0.001385668
Score:  0.696
Data Source:  BioPlex,STRINGDB
FBLIM1
Tbio
Novelty:  0.0332985
p_int:  0.998036292
p_ni:  0.001963708
Score:  0.252
Data Source:  BioPlex,STRINGDB
CLTCL1
Tbio
Novelty:  0.05667807
p_int:  0.997784224
p_ni:  0.002215776
Data Source:  BioPlex
UBB
Tbio
Novelty:  0.00661254
p_int:  0.995864567
p_ni:  0.004135433
Score:  0.172
Data Source:  BioPlex,STRINGDB
PRKAB1
Tchem
Family:  Kinase
Novelty:  0.01610606
p_int:  0.991844952
p_ni:  0.008153308
p_wrong:  0.000001739
Score:  0.56
Data Source:  BioPlex,STRINGDB
GID4
Tbio
Novelty:  0.05252674
p_int:  0.981481436
p_ni:  0.018518564
Data Source:  BioPlex
ARMC8
Tbio
Novelty:  0.06820746
p_int:  0.978821154
p_ni:  0.021178846
Data Source:  BioPlex
ZER1
Tbio
Novelty:  0.02989698
p_int:  0.976720146
p_ni:  0.023279854
Score:  0.173
Data Source:  BioPlex,STRINGDB
PRKAG1
Tchem
Family:  Kinase
Novelty:  0.07735301
p_int:  0.953873813
p_ni:  0.046126187
Score:  0.765
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (12)
Items per page:
1 – 5 of 12
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
2
0
1.1
56.6
3
2
0
1.1
56.6
1
2
0
1.1
55.2
1
2
0
1.1
55.2
visceral adipose tissue measurement
1
1
1
20.9
Items per page:
1 – 5 of 12
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
56.6
0
1.1
56.6
0
1.1
55.2
0
1.1
55.2
visceral adipose tissue measurement
1
20.9
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cutA divalent cation tolerance homolog
VGNC:13796
746949
Macaque
cutA divalent cation tolerance homolog
718364
Mouse
MGI:1914925
67675
Rat
RGD:1303306
294288
Dog
cutA divalent cation tolerance homolog
VGNC:39736
474874
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cutA divalent cation tolerance homolog
Macaque
cutA divalent cation tolerance homolog
Mouse
Rat
Dog
cutA divalent cation tolerance homolog
Publication Statistics
PubMed Score 57.05
PubMed score by year
PubTator Score 11.82
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title