Tbio GAS7 Growth arrest-specific protein 7

Protein Summary

Description

May play a role in promoting maturation and morphological differentiation of cerebellar neurons. Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O60861
• A8KAC2
• B2RCK9
• O43144
• Q53Y77
• Q7Z571
• GAS-7

Gene Name

• GAS7

Ensembl ID

• ENST00000323816
• ENSP00000322608
• ENSG00000007237
• ENST00000432992
• ENSP00000407552
• ENST00000437099
• ENSP00000410108
• ENST00000542249
• ENSP00000443265
• ENST00000579158
• ENSP00000463527
• ENST00000580865
• ENSP00000463873
• ENST00000585266
• ENSP00000464240

Symbol

• KIAA0394

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.88
kinase perturbation	0.76
gene perturbation	0.75
PubMedID	0.71
tissue sample	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 58.98   (req: < 5)

Gene RIFs: 25   (req: <= 3)

Antibodies: 386   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 58.98   (req: >= 5)

Gene RIFs: 25   (req: > 3)

Antibodies: 386   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0