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Tbio
ZNF354A
Zinc finger protein 354A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335815
  • ENSP00000337122
  • ENSG00000169131

Symbol
  • EZNF
  • HKL1
  • TCF17
  • EZNF
  • HKL1
  • KID1
  • KID-1
  • TCF17
  • HEL104
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.79
histone modification site profile
0.69
cell type or tissue
0.59
transcription factor binding site profile
0.59
virus perturbation
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.4   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.4   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
ZC3HAV1
Tbio
Novelty:  0.01357759
p_int:  0.992711063
p_ni:  0.007249263
p_wrong:  0.000039674
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.991160004
p_ni:  0.008839996
Score:  0.962
Data Source:  BioPlex,STRINGDB
GPATCH4
Tdark
Novelty:  1.13040547
p_int:  0.987082458
p_ni:  0.012901588
p_wrong:  0.000015954
Data Source:  BioPlex
ZNF71
Tbio
Family:  TF
Novelty:  0.24703192
p_int:  0.986444688
p_ni:  0.013355481
p_wrong:  0.000199831
Data Source:  BioPlex
PPAN
Tbio
Novelty:  0.01063709
p_int:  0.982952775
p_ni:  0.017042764
p_wrong:  0.00000446
Data Source:  BioPlex
HIST1H1E
Tbio
Novelty:  0.01125284
p_int:  0.982791727
p_ni:  0.01720732
p_wrong:  9.53e-7
Data Source:  BioPlex
RPL11
Tbio
Novelty:  0.00448962
p_int:  0.972875545
p_ni:  0.026905467
p_wrong:  0.000218988
Data Source:  BioPlex
RPL30
Tbio
Novelty:  0.0134194
p_int:  0.967275386
p_ni:  0.032720278
p_wrong:  0.000004336
Score:  0.159
Data Source:  BioPlex,STRINGDB
RPL28
Tbio
Novelty:  0.03136035
p_int:  0.949435201
p_ni:  0.050552622
p_wrong:  0.000012177
Data Source:  BioPlex
ZNF331
Tbio
Family:  TF
Novelty:  0.05976217
p_int:  0.89333229
p_ni:  0.106630411
p_wrong:  0.000037299
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
1
1
1
38.2
granulocyte percentage of myeloid white cells
1
1
1
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
1
38.2
granulocyte percentage of myeloid white cells
1
28.1
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 354A
VGNC:4233
739326
Mouse
MGI:103172
21408
Rat
RGD:2967
24522
Dog
zinc finger protein 354A
VGNC:53505
100688159
Cow
zinc finger protein 354A
524106
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 354A
Mouse
Rat
Dog
zinc finger protein 354A
Cow
zinc finger protein 354A
Publication Statistics
PubMed Score 19.40
PubMed score by year
PubTator Score 5.57
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title