DPM1
Dolichol-phosphate mannosyltransferase subunit 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.95 | ||
histone modification site profile | 0.92 | ||
transcription factor binding site profile | 0.84 | ||
ligand (protein) perturbation | 0.83 | ||
virus perturbation | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Reactome | Defective DPM1 causes DPM1-CDG (CDG-1e) | ||||
Reactome | Defective DPM2 causes DPM2-CDG (CDG-1u) | ||||
Reactome | Defective DPM3 causes DPM3-CDG (CDG-1o) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Defective DPM1 causes DPM1-CDG (CDG-1e) | ||||
Defective DPM2 causes DPM2-CDG (CDG-1u) | ||||
Defective DPM3 causes DPM3-CDG (CDG-1o) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | HGNC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 3 | 6 | 92 | |||||
1 | 1 | 0 | 1.1 | 46.9 | |||||
2 | 2 | 1 | 1.1 | 24.5 | |||||
1 | 1 | 1 | 15.8 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 92 | |||||
0 | 1.1 | 46.9 | |||||
1 | 1.1 | 24.5 | |||||
1 | 15.8 | ||||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | VGNC:13845 | 745025 | |||||
Macaque | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | 701283 | ||||||
Mouse | MGI:1330239 | 13480 | ||||||
Rat | RGD:1310120 | 296394 | ||||||
Dog | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | VGNC:40070 | 477264 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | |||||
Macaque | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | |||||
Mouse | ||||||
Rat | ||||||
Dog | dolichyl-phosphate mannosyltransferase subunit 1, catalytic | |||||
PMID | Year | Title |
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