UGDH
UDP-glucose 6-dehydrogenase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.92 | ||
kinase perturbation | 0.91 | ||
transcription factor perturbation | 0.88 | ||
histone modification site profile | 0.86 | ||
PubMedID | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Formation of the active cofactor, UDP-glucuronate | ||||
Reactome | Glucuronidation | ||||
Reactome | Metabolism | ||||
Reactome | Phase II - Conjugation of compounds | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Formation of the active cofactor, UDP-glucuronate | ||||
Glucuronidation | ||||
Metabolism | ||||
Phase II - Conjugation of compounds | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
alcohol consumption measurement | 13 | 10 | 18 | 8.1 | 98.8 | ||||
alcohol use disorder measurement | 5 | 5 | 2 | 7.9 | 97 | ||||
bitter alcoholic beverage consumption measurement | 1 | 1 | 1 | 80.8 | |||||
serum gamma-glutamyl transferase measurement | 1 | 1 | 1 | 75.6 | |||||
longitudinal alcohol consumption measurement | 1 | 1 | 1 | 71.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
alcohol consumption measurement | 18 | 8.1 | 98.8 | ||||
alcohol use disorder measurement | 2 | 7.9 | 97 | ||||
bitter alcoholic beverage consumption measurement | 1 | 80.8 | |||||
serum gamma-glutamyl transferase measurement | 1 | 75.6 | |||||
longitudinal alcohol consumption measurement | 1 | 71.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | UDP-glucose 6-dehydrogenase | VGNC:2958 | 471171 | |||||
Macaque | UDP-glucose 6-dehydrogenase | 699500 | ||||||
Mouse | MGI:1306785 | 22235 | ||||||
Rat | RGD:621879 | 83472 | ||||||
Dog | UDP-glucose 6-dehydrogenase | VGNC:48117 | 479107 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | UDP-glucose 6-dehydrogenase | |||||
Macaque | UDP-glucose 6-dehydrogenase | |||||
Mouse | ||||||
Rat | ||||||
Dog | UDP-glucose 6-dehydrogenase | |||||
PMID | Year | Title |
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