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Tbio
FOXD2
Forkhead box protein D2

Protein Summary
Description
Probable transcription factor involved in embryogenesis and somatogenesis. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334793
  • ENSP00000335493
  • ENSG00000186564

Symbol
  • FKHL17
  • FREAC9
  • FKHL17
  • FREAC9
  • FREAC-9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.9
tissue sample
0.63
gene perturbation
0.61
histone modification site profile
0.56
PubMedID
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.39   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 110   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.39   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 110   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alopecia
1
1
1
7.2
hippocampal tail volume
1
1
0
7.3
5.7
hematocrit
1
1
1
0.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Alopecia
1
7.2
hippocampal tail volume
0
7.3
5.7
hematocrit
1
0.4
Gene Ontology Terms (9)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Traceable Author Statement (TAS)
ProtInc
Inferred by Curator (IC)
NTNU_SB
Protein-Protein Interactions (26)
1 – 10 of 26
FOXD4
Tbio
Family: TF
Novelty: 0.11166611
p_int: 0.999843495
p_ni: 6.3e-7
p_wrong: 0.000155875
Score: 0.266
Data Source: BioPlex,STRINGDB
CGRRF1
Tdark
Novelty: 0.49690187
p_int: 0.998639059
p_ni: 0.000005144
p_wrong: 0.001355798
Score: 0.227
Data Source: BioPlex,STRINGDB
FOXD4L6
Tdark
Family: TF
Novelty: 9.78461538
p_int: 0.870962776
p_ni: 0.000003141
p_wrong: 0.129034083
Score: 0.209
Data Source: BioPlex,STRINGDB
ATXN7L1
Tdark
Novelty: 0.43694835
Score: 0.636
Data Source: STRINGDB
OTUD7A
Tbio
Novelty: 0.09531354
Score: 0.557
Data Source: STRINGDB
SIX2
Tbio
Family: TF
Novelty: 0.01046481
Score: 0.555
Data Source: STRINGDB
SH2D4A
Tbio
Novelty: 0.12343277
Score: 0.509
Data Source: STRINGDB
ZNF471
Tdark
Family: TF
Novelty: 0.31061952
Score: 0.482
Data Source: STRINGDB
RANBP3L
Tdark
Novelty: 0.35708446
Score: 0.475
Data Source: STRINGDB
ZBTB1
Tbio
Family: TF
Novelty: 0.33667235
Score: 0.473
Data Source: STRINGDB
Publication Statistics
PubMed Score  13.39

PubMed score by year
PubTator Score  8.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer