Tbio STX10 Syntaxin-10

Protein Summary

Description

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

Uniprot Accession IDs

• O60499
• A6NC41
• Q6IAP4
• Q96AE8
• Syn10

Gene Name

• STX10

Ensembl ID

• ENST00000343587
• ENSP00000339350
• ENSG00000104915
• ENST00000587230
• ENSP00000466298

Symbol

• SYN10
• SYN10
• hsyn10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.73
cellular component	0.64
tissue sample	0.59
protein domain	0.58
transcription factor binding site profile	0.58

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Snare Protein / Syntaxin-10

DTO Classes

Protein / Transporter / Snare Protein / Syntaxin-10

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.45   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 138   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.45   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0