ACSL4
Long-chain-fatty-acid--CoA ligase 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.97 | ||
molecular function | 0.91 | ||
microRNA | 0.83 | ||
cellular component | 0.78 | ||
histone modification site profile | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Fatty acid metabolism | ||||
Reactome | Fatty acyl-CoA biosynthesis | ||||
Reactome | Free fatty acids regulate insulin secretion | ||||
Reactome | Integration of energy metabolism | ||||
Reactome | Intracellular metabolism of fatty acids regulates insulin secretion | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Fatty acid metabolism | ||||
Fatty acyl-CoA biosynthesis | ||||
Free fatty acids regulate insulin secretion | ||||
Integration of energy metabolism | ||||
Intracellular metabolism of fatty acids regulates insulin secretion | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | acyl-CoA synthetase long chain family member 4 | VGNC:7793 | 740279 | |||||
Macaque | acyl-CoA synthetase long chain family member 4 | 704908 | ||||||
Mouse | MGI:1354713 | 50790 | ||||||
Rat | RGD:69401 | 113976 | ||||||
Dog | acyl-CoA synthetase long chain family member 4 | VGNC:37534 | 481018 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | acyl-CoA synthetase long chain family member 4 | |||||
Macaque | acyl-CoA synthetase long chain family member 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | acyl-CoA synthetase long chain family member 4 | |||||
PMID | Year | Title |
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