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Tdark
NME2P1
Putative nucleoside diphosphate kinase

Protein Summary
Description
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
Uniprot Accession IDs
Gene Name
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.59
tissue
0.5
interacting protein
0.47
metabolite
0.45
chemical
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
NME3
Tbio
Family:  Kinase
Novelty:  0.05947052
p_int:  0.999994206
p_ni:  0.000005657
p_wrong:  1.36e-7
Data Source:  BioPlex
S100A9
Tchem
Novelty:  0.00185141
p_int:  0.996911238
p_ni:  0.003088762
Data Source:  BioPlex
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
p_int:  0.996724241
p_ni:  0.003275759
Data Source:  BioPlex
MOGAT2
Tchem
Family:  Enzyme
Novelty:  0.06314447
p_int:  0.99393344
p_ni:  0.006066316
p_wrong:  2.44e-7
Data Source:  BioPlex
RNF26
Tbio
Novelty:  0.40088751
p_int:  0.989005588
p_ni:  0.010994412
Data Source:  BioPlex
FAM218A
Tdark
Novelty:  10.69354839
p_int:  0.988007664
p_ni:  0.011991936
p_wrong:  4.01e-7
Data Source:  BioPlex
FOXR2
Tbio
Family:  TF
Novelty:  0.06548862
p_int:  0.987214172
p_ni:  0.012785826
p_wrong:  2e-9
Data Source:  BioPlex
UCP1
Tbio
Novelty:  0.00055954
p_int:  0.987141634
p_ni:  0.012858343
p_wrong:  2.3e-8
Data Source:  BioPlex
NFYA
Tbio
Family:  TF
Novelty:  0.00507094
p_int:  0.987141634
p_ni:  0.012858343
p_wrong:  2.3e-8
Data Source:  BioPlex
NDUFAF5
Tbio
Family:  Enzyme
Novelty:  0.13483499
p_int:  0.986899256
p_ni:  0.013100727
p_wrong:  1.7e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Interconversion of nucleotide di- and triphosphates (R-HSA-499943)

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Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Interconversion of nucleotide di- and triphosphates
Reactome
Metabolism
Reactome
Metabolism of nucleotides
Name
Explore in Pharos
Explore in Source
Interconversion of nucleotide di- and triphosphates
Metabolism
Metabolism of nucleotides
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
No publication or patent stats found
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Related Publications
Items per page:
0 of 0
PMID
Year
Title