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Tchem
MAST3
Microtubule-associated serine/threonine-protein kinase 3

Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.46   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 153   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.46   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 153   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
3
2
3
96.2
sex hormone-binding globulin measurement
2
1
2
85.6
intelligence
1
1
0
6.2
74.3
red blood cell distribution width
1
1
1
43.7
glycine measurement
1
1
1
37.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
3
96.2
sex hormone-binding globulin measurement
2
85.6
intelligence
0
6.2
74.3
red blood cell distribution width
1
43.7
glycine measurement
1
37.8
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (6)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (40)
1 – 10 of 40
PTEN
Tchem
Family: Enzyme
Novelty: 0.00013818
Score: 0.857
Data Source: STRINGDB
ARPP19
Tbio
Novelty: 0.03109958
Score: 0.781
Data Source: STRINGDB
ENSA
Tbio
Novelty: 0.01642444
Score: 0.769
Data Source: STRINGDB
MAGI3
Tbio
Family: Enzyme
Novelty: 0.03968945
Score: 0.755
Data Source: STRINGDB
FAM19A3
Tdark
Novelty: 0.37183557
Score: 0.653
Data Source: STRINGDB
GALNS
Tbio
Family: Enzyme
Novelty: 0.00510529
Score: 0.652
Data Source: STRINGDB
NAIF1
Tbio
Novelty: 0.1179429
Score: 0.649
Data Source: STRINGDB
FBXL7
Tbio
Novelty: 0.10670779
Score: 0.615
Data Source: STRINGDB
GEMIN5
Tbio
Novelty: 0.03683801
Score: 0.606
Data Source: STRINGDB
YJU2
Tdark
Novelty: 0.75647391
Score: 0.603
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.46

PubMed score by year
PubTator Score  7.98

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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