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Tbio
GMFG
Glia maturation factor gamma

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000597595
  • ENSP00000472249
  • ENSG00000130755

Symbol
  • GMF-GAMMA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
transcription factor
0.68
PubMedID
0.65
molecular function
0.63
disease perturbation
0.62


Related Tools
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ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.67   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 192   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.67   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 192   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glia maturation factor gamma
VGNC:7480
456019
Macaque
glia maturation factor gamma
697397
Mouse
MGI:1927135
63986
Rat
RGD:620506
113940
Horse
glia maturation factor gamma
VGNC:18405
100064427
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glia maturation factor gamma
Macaque
glia maturation factor gamma
Mouse
Rat
Horse
glia maturation factor gamma
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-O60234-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (3)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Gene Ontology Terms (13)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (51)
1 – 10 of 51
GMFB
Tbio
Novelty: 0.01531815
p_int: 0.999999923
p_ni: 5e-8
p_wrong: 2.7e-8
Data Source: BioPlex
PRUNE1
Tchem
Novelty: 0.02136836
p_int: 0.999339566
p_ni: 0.000660434
Score: 0.34
Data Source: BioPlex,STRINGDB
LANCL2
Tchem
Novelty: 0.06086418
p_int: 0.959013146
p_ni: 0.040946425
p_wrong: 0.000040429
Score: 0.309
Data Source: BioPlex,STRINGDB
HSPA14
Tbio
Novelty: 0.01714625
p_int: 0.8526645
p_ni: 0.147329835
p_wrong: 0.000005665
Score: 0.199
Data Source: BioPlex,STRINGDB
ACTR2
Tbio
Novelty: 0.00731489
Score: 0.877
Data Source: STRINGDB
LAPTM5
Tbio
Novelty: 0.06809459
Score: 0.765
Data Source: STRINGDB
CD53
Tbio
Novelty: 0.01722633
Score: 0.76
Data Source: STRINGDB
HCLS1
Tbio
Novelty: 0.08304056
Score: 0.736
Data Source: STRINGDB
ARHGDIB
Tbio
Novelty: 0.01139758
Score: 0.733
Data Source: STRINGDB
CD52
Tclin
Novelty: 0.00142013
Score: 0.672
Data Source: STRINGDB
Publication Statistics
PubMed Score  17.67

PubMed score by year
PubTator Score  8.48

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer