Tbio STRN Striatin

Protein Summary

Description

Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling.

Uniprot Accession IDs

• O43815
• Q3KP65
• Q53TQ8
• Q9NP38

Gene Name

• STRN

Ensembl ID

• ENST00000263918
• ENSP00000263918
• ENSG00000115808
• ENST00000379213
• ENSP00000368513

Symbol

• SG2NA
• STRN1
• PPP2R6A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.94
disease perturbation	0.9
histone modification site profile	0.86
microRNA	0.85
protein domain	0.85

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 129.84   (req: < 5)

Gene RIFs: 22   (req: <= 3)

Antibodies: 164   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 129.84   (req: >= 5)

Gene RIFs: 22   (req: > 3)

Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0