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Tbio
SSNA1
Sjoegren syndrome nuclear autoantigen 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322310
  • ENSP00000313752
  • ENSG00000176101

Symbol
  • NA14
  • N14
  • NA14
  • NA-14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.9
histone modification site profile
0.87
transcription factor binding site profile
0.74
transcription factor perturbation
0.74
virus perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.15   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.15   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (20)
AURKA Activation by TPX2 (R-HSA-8854518)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 16
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
AURKA Activation by TPX2
Reactome
Anchoring of the basal body to the plasma membrane
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Name
Explore in Pharos
Explore in Source
AURKA Activation by TPX2
Anchoring of the basal body to the plasma membrane
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
Gene Ontology Terms (10)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
IntAct
Protein-Protein Interactions (152)
1 – 10 of 152
S100A4
Tbio
Novelty: 0.00156469
p_int: 0.999994062
p_ni: 0.000005925
p_wrong: 1.2e-8
Data Source: BioPlex
PSMC5
Tbio
Family: Enzyme
Novelty: 0.01964643
p_int: 0.999985034
p_ni: 0.000014947
p_wrong: 1.9e-8
Score: 0.179
Data Source: BioPlex,STRINGDB
CHCHD4
Tbio
Novelty: 0.01246396
p_int: 0.999425544
p_ni: 0.000455483
p_wrong: 0.000118973
Data Source: BioPlex
CARTPT
Tbio
Novelty: 0.00031238
p_int: 0.942406914
p_ni: 0.00141095
p_wrong: 0.056182136
Data Source: BioPlex
GOPC
Tbio
Novelty: 0.0164207
p_int: 0.93959986
p_ni: 0.000926821
p_wrong: 0.059473319
Data Source: BioPlex
NUP62
Tbio
Novelty: 0.01433478
p_int: 0.897867292
p_ni: 0.004605499
p_wrong: 0.097527209
Data Source: BioPlex
POLR2M
Tbio
Family: Enzyme
Novelty: 0.10421601
p_int: 0.89526148
p_ni: 0.000274166
p_wrong: 0.104464354
Score: 0.209
Data Source: BioPlex,STRINGDB
LCA5
Tbio
Novelty: 0.05221608
p_int: 0.865567395
p_ni: 0.000395819
p_wrong: 0.134036786
Score: 0.577
Data Source: BioPlex,STRINGDB
SCOC
Tbio
Novelty: 0.08538899
p_int: 0.861707439
p_ni: 0.000883025
p_wrong: 0.137409536
Score: 0.157
Data Source: BioPlex,STRINGDB
DGKG
Tbio
Family: Enzyme
Novelty: 0.04706767
p_int: 0.845793276
p_ni: 0.000424486
p_wrong: 0.153782239
Data Source: BioPlex
Publication Statistics
PubMed Score  61.15

PubMed score by year
PubTator Score  95.02

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer