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Tbio
SSNA1
Sjoegren syndrome nuclear autoantigen 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322310
  • ENSP00000313752
  • ENSG00000176101

Symbol
  • NA14
  • N14
  • NA14
  • NA-14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.9
histone modification site profile
0.87
transcription factor binding site profile
0.74
transcription factor perturbation
0.74
virus perturbation
0.68


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.6   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.6   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
3
3
4
89.1
creatinine measurement
1
2
2
86.1
reticulocyte measurement
3
1
3
82.3
reticulocyte count
6
1
6
80.4
serum urea measurement
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
4
89.1
creatinine measurement
2
86.1
reticulocyte measurement
3
82.3
reticulocyte count
6
80.4
serum urea measurement
1
54.4
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SS nuclear autoantigen 1
VGNC:10452
465173
Mouse
MGI:1915725
68475
Rat
RGD:1310259
311802
Dog
SS nuclear autoantigen 1
VGNC:46835
480666
Horse
SS nuclear autoantigen 1
VGNC:23611
100147202
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SS nuclear autoantigen 1
Mouse
Rat
Dog
SS nuclear autoantigen 1
Horse
SS nuclear autoantigen 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O43805-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (20)
AURKA Activation by TPX2 (R-HSA-8854518)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 16
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
AURKA Activation by TPX2
Reactome
Anchoring of the basal body to the plasma membrane
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Name
Explore in Pharos
Explore in Source
AURKA Activation by TPX2
Anchoring of the basal body to the plasma membrane
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
Gene Ontology Terms (10)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
IntAct
Protein-Protein Interactions (152)
1 – 10 of 152
S100A4
Tchem
Novelty:  0.00136919
p_int:  0.999994062
p_ni:  0.000005925
p_wrong:  1.2e-8
Data Source:  BioPlex
PSMC5
Tbio
Family:  Enzyme
Novelty:  0.01634039
p_int:  0.999985034
p_ni:  0.000014947
p_wrong:  1.9e-8
Score:  0.179
Data Source:  BioPlex,STRINGDB
CHCHD4
Tbio
Novelty:  0.01204944
p_int:  0.999425544
p_ni:  0.000455483
p_wrong:  0.000118973
Data Source:  BioPlex
CARTPT
Tbio
Novelty:  0.00224864
p_int:  0.942406914
p_ni:  0.00141095
p_wrong:  0.056182136
Data Source:  BioPlex
GOPC
Tbio
Novelty:  0.01110168
p_int:  0.93959986
p_ni:  0.000926821
p_wrong:  0.059473319
Data Source:  BioPlex
NUP62
Tbio
Novelty:  0.01432724
p_int:  0.897867292
p_ni:  0.004605499
p_wrong:  0.097527209
Data Source:  BioPlex
POLR2M
Tbio
Family:  Enzyme
Novelty:  0.11413088
p_int:  0.89526148
p_ni:  0.000274166
p_wrong:  0.104464354
Score:  0.209
Data Source:  BioPlex,STRINGDB
LCA5
Tbio
Novelty:  0.0379066
p_int:  0.865567395
p_ni:  0.000395819
p_wrong:  0.134036786
Score:  0.577
Data Source:  BioPlex,STRINGDB
SCOC
Tbio
Novelty:  0.05277646
p_int:  0.861707439
p_ni:  0.000883025
p_wrong:  0.137409536
Score:  0.157
Data Source:  BioPlex,STRINGDB
DGKG
Tbio
Family:  Enzyme
Novelty:  0.03666646
p_int:  0.845793276
p_ni:  0.000424486
p_wrong:  0.153782239
Data Source:  BioPlex
Publication Statistics
PubMed Score  38.60

PubMed score by year
PubTator Score  95.02

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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