Tbio TRAPPC3 Trafficking protein particle complex subunit 3

Protein Summary

Description

May play a role in vesicular transport from endoplasmic reticulum to Golgi. This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Accession IDs

• O43617
• A6NDN0
• B2RDN2
• D3DPS2

Gene Name

• TRAPPC3

Ensembl ID

• ENST00000373162
• ENSP00000362256
• ENSG00000054116
• ENST00000373163
• ENSP00000362257
• ENST00000373166
• ENSP00000362261
• ENST00000617904
• ENSP00000480648

Symbol

• BET3
• BET3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
co-expressed gene	0.99
transcription factor binding site profile	0.96
kinase perturbation	0.95
interacting protein	0.94

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.63   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 201   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.63   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 201   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0