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Tbio
TRAPPC3
Trafficking protein particle complex subunit 3

Protein Summary
Description
May play a role in vesicular transport from endoplasmic reticulum to Golgi. This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373162
  • ENSP00000362256
  • ENSG00000054116
  • ENST00000373163
  • ENSP00000362257
  • ENST00000373166
  • ENSP00000362261
  • ENST00000617904
  • ENSP00000480648

Symbol
  • BET3
  • BET3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
co-expressed gene
0.99
transcription factor binding site profile
0.96
kinase perturbation
0.95
interacting protein
0.94


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 109.1   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 201   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 109.1   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 201   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (4)
1 – 4 of 4
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (10)
Asparagine N-linked glycosylation (R-HSA-446203)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Asparagine N-linked glycosylation
Reactome
COPII-mediated vesicle transport
Reactome
ER to Golgi Anterograde Transport
Reactome
Membrane Trafficking
Reactome
Metabolism of proteins
Name
Explore in Pharos
Explore in Source
Asparagine N-linked glycosylation
COPII-mediated vesicle transport
ER to Golgi Anterograde Transport
Membrane Trafficking
Metabolism of proteins
Gene Ontology Terms (10)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (115)
1 – 10 of 115
TRAPPC5
Tdark
Novelty: 1.63636364
p_int: 0.999999185
p_ni: 8.14e-7
p_wrong: 1e-9
Score: 0.999
Data Source: BioPlex,STRINGDB
TRAPPC1
Tbio
Novelty: 0.1875
p_int: 0.99998851
p_ni: 0.00001149
Score: 0.999
Data Source: BioPlex,STRINGDB
TRAPPC2
Tbio
Novelty: 0.01745001
p_int: 0.999982263
p_ni: 0.000017737
Score: 0.999
Data Source: BioPlex,STRINGDB
TRAPPC12
Tbio
Novelty: 0.05825243
p_int: 0.997958493
p_ni: 0.002041507
Score: 0.993
Data Source: BioPlex,STRINGDB
STMN4
Tbio
Novelty: 0.00798494
p_int: 0.995485056
p_ni: 0.004514944
Score: 0.81
Data Source: BioPlex,STRINGDB
TBC1D14
Tbio
Novelty: 0.30090271
p_int: 0.993655677
p_ni: 0.006344323
Score: 0.824
Data Source: BioPlex,STRINGDB
BCL2L14
Tbio
Novelty: 0.04767234
p_int: 0.993653018
p_ni: 0.006346981
p_wrong: 1e-9
Score: 0.849
Data Source: BioPlex,STRINGDB
RAB43
Tbio
Family: Enzyme
Novelty: 0.02494975
p_int: 0.987945017
p_ni: 0.012054944
p_wrong: 3.9e-8
Score: 0.516
Data Source: BioPlex,STRINGDB
KANK4
Tdark
Novelty: 0.29411765
p_int: 0.970029287
p_ni: 0.029970713
Score: 0.811
Data Source: BioPlex,STRINGDB
GLB1
Tchem
Family: Enzyme
Novelty: 0.00274332
p_int: 0.966443845
p_ni: 0.033556155
Score: 0.735
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  109.10

PubMed score by year
PubTator Score  103.81

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer