AKR7A2
Aflatoxin B1 aldehyde reductase member 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.93 | ||
virus perturbation | 0.9 | ||
co-expressed gene | 0.89 | ||
histone modification site profile | 0.87 | ||
kinase perturbation | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Aflatoxin activation and detoxification | ||||
Reactome | Biological oxidations | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Aflatoxin activation and detoxification | ||||
Biological oxidations | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 2 | 2 | 89.6 | |||||
urinary metabolite measurement | 1 | 1 | 1 | 77.7 | |||||
viral load | 1 | 1 | 1 | 68.6 | |||||
BMI-adjusted hip circumference | 1 | 3 | 3 | 62 | |||||
platelet count | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 89.6 | |||||
urinary metabolite measurement | 1 | 77.7 | |||||
viral load | 1 | 68.6 | |||||
BMI-adjusted hip circumference | 3 | 62 | |||||
platelet count | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | aldo-keto reductase family 7 member A2 | VGNC:11732 | 748767 | |||||
Macaque | aflatoxin B1 aldehyde reductase member 3 | 715623 | ||||||
Mouse | MGI:107796 | 110198 | ||||||
Rat | RGD:620311 | 171445 | ||||||
Dog | aldo-keto reductase family 7 member A2 | 478210 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | aldo-keto reductase family 7 member A2 | |||||
Macaque | aflatoxin B1 aldehyde reductase member 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | aldo-keto reductase family 7 member A2 | |||||
PMID | Year | Title |
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