Tbio TXNL1 Thioredoxin-like protein 1

Protein Summary

Description

Active thioredoxin with a redox potential of about -250 mV.

Uniprot Accession IDs

• O43396

Gene Name

• TXNL1

Ensembl ID

• ENST00000217515
• ENSP00000217515
• ENSG00000091164
• ENST00000590954
• ENSP00000464918

Symbol

• TRP32
• TXL
• TXNL
• Txl
• TXNL
• TRP32
• TXL-1
• HEL-S-114

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
virus perturbation	0.99
kinase perturbation	0.88
protein domain	0.85
transcription factor binding site profile	0.8

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 86.27   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 193   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 86.27   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 193   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0