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Tbio
HSPA12A
Heat shock 70 kDa protein 12A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369209
  • ENSP00000358211
  • ENSG00000165868

Symbol
  • KIAA0417
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.88
histone modification site profile
0.75
molecular function
0.73
microRNA
0.63
transcription factor perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.09   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.09   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (4)
Cellular response to heat stress (R-HSA-3371556)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cellular response to heat stress
Reactome
Cellular responses to external stimuli
Reactome
Cellular responses to stress
Reactome
Regulation of HSF1-mediated heat shock response
Name
Explore in Pharos
Explore in Source
Cellular response to heat stress
Cellular responses to external stimuli
Cellular responses to stress
Regulation of HSF1-mediated heat shock response
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (141)
1 – 10 of 141
TMEM51
Tdark
Novelty: 1.41176471
p_int: 0.999774355
p_ni: 0.000225644
p_wrong: 1e-9
Data Source: BioPlex
PODXL
Tbio
Novelty: 0.00356146
p_int: 0.999577225
p_ni: 0.000422775
Score: 0.162
Data Source: BioPlex,STRINGDB
EPB41L3
Tbio
Novelty: 0.00828944
p_int: 0.999140171
p_ni: 0.000859828
p_wrong: 1e-9
Data Source: BioPlex
LAMP2
Tbio
Novelty: 0.00223951
p_int: 0.997183281
p_ni: 0.002816719
Score: 0.182
Data Source: BioPlex,STRINGDB
FAM174A
Tdark
Novelty: 0.44599913
p_int: 0.989182467
p_ni: 0.01081753
p_wrong: 3e-9
Data Source: BioPlex
LAMP3
Tbio
Novelty: 0.02024311
p_int: 0.987769535
p_ni: 0.012230465
Score: 0.186
Data Source: BioPlex,STRINGDB
DKKL1
Tbio
Novelty: 0.00579782
p_int: 0.9651282
p_ni: 0.034871699
p_wrong: 1.01e-7
Data Source: BioPlex
TNF
Tclin
Novelty: 0.00001974
p_int: 0.956488665
p_ni: 0.043511328
p_wrong: 7e-9
Data Source: BioPlex
BSG
Tbio
Novelty: 0.00077805
p_int: 0.902147193
p_ni: 0.097852803
p_wrong: 4e-9
Data Source: BioPlex
CCL22
Tbio
Novelty: 0.00323984
p_int: 0.898999804
p_ni: 0.101000009
p_wrong: 1.88e-7
Data Source: BioPlex
Publication Statistics
PubMed Score  6.09

PubMed score by year
PubTator Score  2.89

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer