Tbio CYB5B Cytochrome b5 type B

Protein Summary

Description

Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.

Uniprot Accession IDs

• O43169
• A8K6B1
• Q96CC3
• Q9BT35

Gene Name

• CYB5B

Ensembl ID

• ENST00000512062
• ENSP00000423679
• ENSG00000103018

Symbol

• CYB5M
• OMB5
• OMB5
• CYB5-M
• CYPB5M

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.95
histone modification site profile	0.88
transcription factor binding site profile	0.88
transcription factor perturbation	0.88
kinase perturbation	0.81

Protein Classes

PANTHER Classes

Protein / Oxidoreductase / Oxidase / Cytochrome B5 Type B

DTO Classes

Protein / Enzyme / Oxidoreductase / Oxidase / Cytochrome B5 Type B

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.46   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.46   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0