TET3
Methylcytosine dioxygenase TET3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.79 | ||
biological process | 0.73 | ||
cell line | 0.68 | ||
small molecule perturbation | 0.63 | ||
microRNA | 0.59 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | TET1,2,3 and TDG demethylate DNA | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
TET1,2,3 and TDG demethylate DNA | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 2 | 0 | 1.3 | 79.5 | |||||
eosinophil count | 2 | 2 | 2 | 66.6 | |||||
risk-taking behaviour | 2 | 1 | 2 | 57.3 | |||||
alcohol consumption measurement | 2 | 1 | 2 | 56.2 | |||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 56 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.3 | 79.5 | |||||
eosinophil count | 2 | 66.6 | |||||
risk-taking behaviour | 2 | 57.3 | |||||
alcohol consumption measurement | 2 | 56.2 | |||||
eosinophil percentage of leukocytes | 1 | 56 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 3 | VGNC:10784 | 459329 | |||||
Macaque | tet methylcytosine dioxygenase 3 | 707759 | ||||||
Mouse | MGI:2446229 | 194388 | ||||||
Rat | RGD:1590584 | 680576 | ||||||
Dog | tet methylcytosine dioxygenase 3 | VGNC:47262 | 483109 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tet methylcytosine dioxygenase 3 | |||||
Macaque | tet methylcytosine dioxygenase 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tet methylcytosine dioxygenase 3 | |||||
PMID | Year | Title |
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