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Tbio
NUPL2
Nucleoporin-like protein 2

Protein Summary
Description
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258742
  • ENSP00000258742
  • ENSG00000136243
  • ENST00000438012
  • ENSP00000415511

Symbol
  • CG1
  • CG1
  • hCG1
  • NLP-1
  • NLP_1
  • NUPL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.99
kinase perturbation
0.88
transcription factor binding site profile
0.75
biological process
0.68
histone modification site profile
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.1   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 111   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.1   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0