Protein Summary
Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
- ENST00000353656
- ENSP00000487294
- ENSG00000056998
- ENST00000381163
- ENSP00000370555
- ENST00000398806
- ENSP00000381786
- GN2
- GN-2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.73 | ||
tissue | 0.56 | ||
cell line | 0.5 | ||
small molecule perturbation | 0.48 | ||
microRNA | 0.46 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 69.05 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 160 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 69.05 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 160 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (63)
STBD1
Novelty: 0.08362185
p_int: 0.999999332
p_ni: 6.29e-7
p_wrong: 3.9e-8
Score: 0.605
Data Source: BioPlex,STRINGDB
OSCP1
Novelty: 0.05361924
p_int: 0.999993651
p_ni: 0.000006329
p_wrong: 2.1e-8
Score: 0.816
Data Source: BioPlex,STRINGDB
DACH2
Novelty: 0.0806643
p_int: 0.999982445
p_ni: 0.000017553
p_wrong: 3e-9
Score: 0.187
Data Source: BioPlex,STRINGDB
GYS1
Family: Enzyme
Novelty: 0.00721964
p_int: 0.999958277
p_ni: 0.000041723
Score: 0.996
Data Source: BioPlex,STRINGDB
AMY2A
Family: Enzyme
Novelty: 0.00132709
p_int: 0.99993328
p_ni: 0.000028788
p_wrong: 0.000037932
Score: 0.172
Data Source: BioPlex,STRINGDB
NONO
Novelty: 0.00501502
p_int: 0.99989458
p_ni: 0.000105293
p_wrong: 1.27e-7
Score: 0.177
Data Source: BioPlex,STRINGDB
GYG1
Family: Enzyme
Novelty: 0.01446978
p_int: 0.998748705
p_ni: 0.001251295
Score: 0.968
Data Source: BioPlex,STRINGDB
SIRT5
Family: Epigenetic
Novelty: 0.00225239
p_int: 0.995233294
p_ni: 0.004766704
p_wrong: 2e-9
Score: 0.17
Data Source: BioPlex,STRINGDB
RAE1
Novelty: 0.01342883
p_int: 0.990452976
p_ni: 0.009547024
Score: 0.163
Data Source: BioPlex,STRINGDB
SLC16A10
Family: Transporter
Novelty: 0.02363735
p_int: 0.98690382
p_ni: 0.012787982
p_wrong: 0.000308197
Score: 0.173
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (16)
Reactome (11)
KEGG (2)
UniProt (1)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of carbohydrate metabolism | ||||
Reactome | Diseases of metabolism | ||||
Reactome | Glycogen breakdown (glycogenolysis) | ||||
Reactome | Glycogen metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Diseases of carbohydrate metabolism | ||||
Diseases of metabolism | ||||
Glycogen breakdown (glycogenolysis) | ||||
Glycogen metabolism | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Disease Associations ()
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 2 | 6 | 81.8 | |||||
low density lipoprotein cholesterol measurement | 1 | 1 | 1 | 77.1 | |||||
body height | 2 | 1 | 2 | 52.7 | |||||
mean corpuscular volume | 1 | 1 | 1 | 7.6 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 6 | 81.8 | |||||
low density lipoprotein cholesterol measurement | 1 | 77.1 | |||||
body height | 2 | 52.7 | |||||
mean corpuscular volume | 1 | 7.6 | |||||
Find similar targets by:
IDG Resources
Orthologs (5)
1 – 5 of 5
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glycogenin 2 | VGNC:12391 | 465469 | |||||
Macaque | glycogenin 2 | 720568 | ||||||
Dog | glycogenin 2 | VGNC:41573 | 491717 | |||||
Horse | glycogenin 2 | VGNC:18669 | 100064536 | |||||
Cow | glycogenin 2 | VGNC:29729 | 505258 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glycogenin 2 | |||||
Macaque | glycogenin 2 | |||||
Dog | glycogenin 2 | |||||
Horse | glycogenin 2 | |||||
Cow | glycogenin 2 | |||||
Publication Statistics
PubMed Score 69.05
PubMed score by year
PubTator Score 37.45
PubTator score by year
Related Publications
Text Mined References (14)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
---|