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Tdark
TM9SF1
Transmembrane 9 superfamily member 1

Protein Classes
Protein Summary
Description
Plays an essential role in autophagy.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261789
  • ENSP00000261789
  • ENSG00000100926
  • ENST00000396854
  • ENSP00000380063
  • ENST00000646500
  • ENSP00000494851
  • ENSG00000285465
  • ENST00000646762
  • ENSP00000494320

Symbol
  • MP70
  • HMP70
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.99
kinase perturbation
0.96
histone modification site profile
0.9
interacting protein
0.89
transcription factor binding site profile
0.71


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 239   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 239   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O15321-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (60)
1 – 10 of 60
BTNL3
Tdark
Novelty: 0.27343899
p_int: 0.832878021
p_ni: 0.167121979
Data Source: BioPlex
CLEC2D
Tbio
Novelty: 0.02501194
p_int: 0.752199467
p_ni: 0.247800533
Data Source: BioPlex
CHMP2A
Tbio
Novelty: 0.00169253
Score: 0.882
Data Source: STRINGDB
TMEM174
Tdark
Novelty: 0.40496536
Score: 0.805
Data Source: STRINGDB
NSA2
Tbio
Novelty: 0.04542275
Score: 0.796
Data Source: STRINGDB
CHMP5
Tbio
Novelty: 0.03378716
Score: 0.791
Data Source: STRINGDB
CUL5
Tbio
Novelty: 0.00792494
Score: 0.776
Data Source: STRINGDB
CUL3
Tbio
Novelty: 0.0028737
Score: 0.751
Data Source: STRINGDB
CUL1
Tbio
Novelty: 0.00244476
Score: 0.751
Data Source: STRINGDB
CACUL1
Tbio
Novelty: 0.17361884
Score: 0.751
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.76

PubMed score by year
PubTator Score  4.41

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer