GRM6
Metabotropic glutamate receptor 6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.97 | ||
tissue sample | 0.72 | ||
ligand (chemical) | 0.7 | ||
cellular component | 0.68 | ||
PubMedID | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | GPCR ligand binding | ||||
Reactome | Signal Transduction | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
GPCR ligand binding | ||||
Signal Transduction | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 1 | 1 | 1 | 59 | |||||
refractive error measurement | 1 | 1 | 1 | 31.4 | |||||
waist circumference | 1 | 1 | 1 | 21.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 1 | 59 | |||||
refractive error measurement | 1 | 31.4 | |||||
waist circumference | 1 | 21.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glutamate metabotropic receptor 6 | VGNC:8623 | 462323 | |||||
Macaque | glutamate metabotropic receptor 6 | 713339 | ||||||
Mouse | MGI:1351343 | 108072 | ||||||
Rat | RGD:2747 | 24419 | ||||||
Dog | glutamate metabotropic receptor 6 | VGNC:41513 | 481452 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glutamate metabotropic receptor 6 | |||||
Macaque | glutamate metabotropic receptor 6 | |||||
Mouse | ||||||
Rat | ||||||
Dog | glutamate metabotropic receptor 6 | |||||
PMID | Year | Title |
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