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Tbio
ZNF185
Zinc finger protein 185

Protein Summary
Description
May be involved in the regulation of cellular proliferation and/or differentiation. Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318504
  • ENSP00000312782
  • ENSG00000147394
  • ENST00000318529
  • ENSP00000313919
  • ENST00000324823
  • ENSP00000325307
  • ENST00000370268
  • ENSP00000359291
  • ENST00000370270
  • ENSP00000359293
  • ENST00000449285
  • ENSP00000395228
  • ENST00000454925
  • ENSP00000392984
  • ENST00000535861
  • ENSP00000440847
  • ENST00000539731
  • ENSP00000444367

Symbol
  • SCELL
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.91
cellular component
0.67
tissue
0.62
microRNA
0.6
transcription factor
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 379.52   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 379.52   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0