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Tbio
VILL
Villin-like protein

Protein Summary
Description
Possible tumor suppressor. The protein encoded by this gene belongs to the villin/gelsolin family. It contains 6 gelsolin-like repeats and a headpiece domain. It may play a role in actin-bundling. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000283713
  • ENSP00000283713
  • ENSG00000136059
  • ENST00000383759
  • ENSP00000373266
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.77
protein domain
0.73
tissue sample
0.66
PubMedID
0.57
cellular component
0.55


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.83   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.83   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
villin like
VGNC:12231
460266
Macaque
villin like
696988
Mouse
MGI:1201781
22351
Rat
RGD:1304843
301057
Dog
villin like
VGNC:48262
485585
Species
Name
OMA
EggNOG
Inparanoid
Chimp
villin like
Macaque
villin like
Mouse
Rat
Dog
villin like
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (32)
1 – 10 of 32
HSPA8
Tchem
Novelty: 0.00081014
p_int: 0.986441463
p_ni: 0.013558537
Data Source: BioPlex
TIMM13
Tdark
Family: Enzyme
Novelty: 0.04802297
p_int: 0.908475132
p_ni: 0.091524868
Score: 0.379
Data Source: BioPlex,STRINGDB
HSPA6
Tbio
Novelty: 0.00654285
p_int: 0.79038088
p_ni: 0.20961912
Score: 0.221
Data Source: BioPlex,STRINGDB
APRG1
Tdark
Novelty: 0.53797468
Score: 0.669
Data Source: STRINGDB
NPRL2
Tbio
Family: Enzyme
Novelty: 0.02848752
Score: 0.636
Data Source: STRINGDB
MAPKAPK3
Tchem
Family: Kinase
Novelty: 0.02469147
Score: 0.599
Data Source: STRINGDB
CTDSPL
Tbio
Family: Enzyme
Novelty: 0.00471423
Score: 0.596
Data Source: STRINGDB
GUSB
Tchem
Family: Enzyme
Novelty: 0.00053974
Score: 0.555
Data Source: STRINGDB
GMFB
Tbio
Novelty: 0.01531815
Score: 0.548
Data Source: STRINGDB
PLCD1
Tchem
Family: Enzyme
Novelty: 0.00742197
Score: 0.544
Data Source: STRINGDB
Publication Statistics
PubMed Score  22.83

PubMed score by year
PubTator Score  41.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer