Tbio PGRMC2 Membrane-associated progesterone receptor component 2

Protein Summary

Description

Receptor for steroids.

Uniprot Accession IDs

• O15173
• Q569H1

Gene Name

• PGRMC2

Ensembl ID

• ENST00000296425
• ENSP00000296425
• ENSG00000164040
• ENST00000520121
• ENSP00000429301
• ENST00000613358
• ENSP00000481886

Symbol

• DG6
• PMBP
• DG6
• PMBP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.99
disease perturbation	0.96
drug perturbation	0.87
ligand (protein) perturbation	0.83
microRNA	0.83

Protein Classes

PANTHER Classes

Protein / Signaling Molecule / Membrane-associated Progesterone Receptor Component 2

Protein / Receptor / Membrane-associated Progesterone Receptor Component 2

DTO Classes

Protein / Signaling / Membrane-associated Progesterone Receptor Component 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 125.77   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 254   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 125.77   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 254   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0