MUSK
Muscle, skeletal receptor tyrosine-protein kinase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
molecular function | 0.98 | ||
biological process | 0.82 | ||
trait | 0.75 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ECM proteoglycans | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ECM proteoglycans | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
eosinophil count | 3 | 2 | 3 | 94 | |||||
eosinophil percentage of leukocytes | 2 | 2 | 2 | 92.6 | |||||
central corneal thickness | 2 | 1 | 0 | 2.8 | 73.7 | ||||
heel bone mineral density | 2 | 2 | 3 | 73.2 | |||||
sum of eosinophil and basophil counts | 1 | 1 | 1 | 68.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 3 | 94 | |||||
eosinophil percentage of leukocytes | 2 | 92.6 | |||||
central corneal thickness | 0 | 2.8 | 73.7 | ||||
heel bone mineral density | 3 | 73.2 | |||||
sum of eosinophil and basophil counts | 1 | 68.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | muscle associated receptor tyrosine kinase | VGNC:10127 | 464653 | |||||
Macaque | muscle associated receptor tyrosine kinase | 709397 | ||||||
Mouse | MGI:103581 | 18198 | ||||||
Rat | RGD:3211 | 81725 | ||||||
Horse | muscle associated receptor tyrosine kinase | VGNC:20446 | 100058619 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | muscle associated receptor tyrosine kinase | |||||
Macaque | muscle associated receptor tyrosine kinase | |||||
Mouse | ||||||
Rat | ||||||
Horse | muscle associated receptor tyrosine kinase | |||||
PMID | Year | Title |
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