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Tbio
U2SURP
U2 snRNP-associated SURP motif-containing protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000473835
  • ENSP00000418563
  • ENSG00000163714

Symbol
  • KIAA0332
  • SR140
  • SR140
  • fSAPa
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
transcription factor perturbation
0.97
transcription factor binding site profile
0.92
histone modification site profile
0.86
co-expressed gene
0.85


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.26   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 123   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.26   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (232)
RBM17
Tbio
Novelty:  0.04840999
p_int:  0.999976791
p_ni:  0.000023209
Score:  0.985
Data Source:  BioPlex,STRINGDB
PLOD1
Tbio
Family:  Enzyme
Novelty:  0.00905345
p_int:  0.997504079
p_ni:  0.002495921
Data Source:  BioPlex
SNRPE
Tbio
Novelty:  0.02033423
p_int:  0.992792453
p_ni:  0.007207547
Score:  0.934
Data Source:  BioPlex,STRINGDB
PHF5A
Tbio
Family:  Epigenetic
Novelty:  0.02989472
p_int:  0.983286308
p_ni:  0.016713691
Score:  0.914
Data Source:  BioPlex,STRINGDB
FGFR2
Tclin
Family:  Kinase
Novelty:  0.00066613
p_int:  0.982193566
p_ni:  0.017806434
Data Source:  BioPlex
CSTF2T
Tbio
Novelty:  0.11811814
p_int:  0.974643906
p_ni:  0.025356092
p_wrong:  2e-9
Score:  0.919
Data Source:  BioPlex,STRINGDB
SFSWAP
Tdark
Novelty:  0.2236256
p_int:  0.969198955
p_ni:  0.030801045
Score:  0.712
Data Source:  BioPlex,STRINGDB
WDFY2
Tbio
Novelty:  0.01835759
p_int:  0.964361869
p_ni:  0.035638131
Score:  0.324
Data Source:  BioPlex,STRINGDB
ZRSR2
Tbio
Novelty:  0.03449891
p_int:  0.939607217
p_ni:  0.060392783
Score:  0.638
Data Source:  BioPlex,STRINGDB
SNRPB2
Tbio
Novelty:  0.17219587
p_int:  0.930657098
p_ni:  0.069342902
Score:  0.919
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Metabolism of RNA (R-HSA-8953854)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
mRNA Splicing
Reactome
mRNA Splicing - Major Pathway
Name
Explore in Pharos
Explore in Source
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
2
3
3
86.9
mean platelet volume
2
2
2
78.3
low density lipoprotein cholesterol measurement
3
2
3
73
triglyceride measurement
4
4
4
66.3
red blood cell distribution width
2
2
2
64.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
3
86.9
mean platelet volume
2
78.3
low density lipoprotein cholesterol measurement
3
73
triglyceride measurement
4
66.3
red blood cell distribution width
2
64.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1915208
67958
Rat
RGD:1307882
315903
Dog
U2 snRNP associated SURP domain containing
VGNC:48033
477103
Horse
U2 snRNP associated SURP domain containing
VGNC:24697
100051188
Cow
U2 snRNP associated SURP domain containing
VGNC:36557
505019
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
U2 snRNP associated SURP domain containing
Horse
U2 snRNP associated SURP domain containing
Cow
U2 snRNP associated SURP domain containing
Publication Statistics
PubMed Score 5.26
PubMed score by year
PubTator Score 0.45
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title