Tdark KHNYN Protein KHNYN

Protein Summary

Description

This gene encodes a protein containing a ribonuclease NYN domain. The function of this protein has yet to be determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot Accession IDs

• O15037
• Q86TZ6
• Q8IUQ2
• Q96BA9

Gene Name

• KHNYN

Ensembl ID

• ENST00000251343
• ENSP00000251343
• ENSG00000100441
• ENST00000553935
• ENSP00000450799
• ENST00000556842
• ENSP00000451106

Symbol

• KIAA0323
• KIAA0323

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.67
transcription factor	0.65
tissue sample	0.64
microRNA	0.62
co-expressed gene	0.61

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Protein Khnyn

DTO Classes

Protein / Nucleic Acid Binding / Protein Khnyn

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.97   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 76   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.97   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0