PHYH
Phytanoyl-CoA dioxygenase, peroxisomal
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
kinase perturbation | 0.98 | ||
transcription factor perturbation | 0.98 | ||
molecular function | 0.76 | ||
cellular component | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Alpha-oxidation of phytanate | ||||
Reactome | Fatty acid metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Peroxisomal lipid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Alpha-oxidation of phytanate | ||||
Fatty acid metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Peroxisomal lipid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 2 | 3 | 71.6 | |||||
Abdominal symptom | 1 | 1 | 0 | 2.5 | 17.8 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 71.6 | |||||
Abdominal symptom | 0 | 2.5 | 17.8 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phytanoyl-CoA 2-hydroxylase | VGNC:7248 | 450310 | |||||
Macaque | phytanoyl-CoA 2-hydroxylase | 695915 | ||||||
Mouse | MGI:891978 | 16922 | ||||||
Rat | RGD:620317 | 114209 | ||||||
Dog | phytanoyl-CoA hydroxylase-like | 478000 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phytanoyl-CoA 2-hydroxylase | |||||
Macaque | phytanoyl-CoA 2-hydroxylase | |||||
Mouse | ||||||
Rat | ||||||
Dog | phytanoyl-CoA hydroxylase-like | |||||
PMID | Year | Title |
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