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Tdark
ZNF213
Zinc finger protein 213

Protein Summary
Description
May be involved in transcriptional regulation. C2H2 zinc finger proteins, such as ZNF213, have bipartite structures in which one domain binds DNA or RNA and the other modulates target gene expression.[supplied by OMIM, Apr 2004]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000396878
  • ENSP00000380087
  • ENSG00000085644
  • ENST00000416391
  • ENSP00000403892
  • ENST00000574902
  • ENSP00000460157
  • ENST00000576416
  • ENSP00000459177

Symbol
  • ZKSCAN21
  • CR53
  • ZSCAN53
  • ZKSCAN21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
histone modification site profile
0.83
tissue sample
0.75
transcription factor binding site profile
0.68
transcription factor
0.67


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 154   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 154   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 213
VGNC:13815
453858
Macaque
zinc finger protein 213
700976
Mouse
MGI:3053094
449521
Rat
RGD:1305919
287094
Horse
zinc finger protein 213
VGNC:25279
102149130
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 213
Macaque
zinc finger protein 213
Mouse
Rat
Horse
zinc finger protein 213
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O14771-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (32)
1 – 10 of 32
ZSCAN32
Tdark
Family: TF
Novelty: 3.83392226
p_int: 0.999996344
p_ni: 0.000003578
p_wrong: 7.8e-8
Score: 0.827
Data Source: BioPlex,STRINGDB
ZSCAN20
Tdark
Family: TF
Novelty: 0.37441538
p_int: 0.999996338
p_ni: 0.000003639
p_wrong: 2.4e-8
Score: 0.71
Data Source: BioPlex,STRINGDB
ZNF232
Tdark
Family: TF
Novelty: 0.68288358
p_int: 0.999996321
p_ni: 0.000003621
p_wrong: 5.7e-8
Score: 0.679
Data Source: BioPlex,STRINGDB
SUFU
Tbio
Novelty: 0.00475249
p_int: 0.99998709
p_ni: 0.000012902
p_wrong: 8e-9
Score: 0.158
Data Source: BioPlex,STRINGDB
ZNF174
Tbio
Family: TF
Novelty: 0.05970272
p_int: 0.999932634
p_ni: 0.000057264
p_wrong: 0.000010102
Score: 0.193
Data Source: BioPlex,STRINGDB
SCAND1
Tbio
Novelty: 0.06863895
p_int: 0.999893245
p_ni: 0.000106746
p_wrong: 8e-9
Data Source: BioPlex
GNE
Tbio
Family: Enzyme
Novelty: 0.00285751
p_int: 0.999514229
p_ni: 0.000484464
p_wrong: 0.000001307
Data Source: BioPlex
ZSCAN1
Tbio
Family: TF
Novelty: 0.0217244
p_int: 0.999313177
p_ni: 0.000023923
p_wrong: 0.0006629
Score: 0.71
Data Source: BioPlex,STRINGDB
ZNF397
Tbio
Family: TF
Novelty: 0.60034816
p_int: 0.996262207
p_ni: 0.003448529
p_wrong: 0.000289264
Score: 0.808
Data Source: BioPlex,STRINGDB
ZSCAN21
Tbio
Family: TF
Novelty: 0.18025344
p_int: 0.994623581
p_ni: 0.005369186
p_wrong: 0.000007233
Data Source: BioPlex
Publication Statistics
PubMed Score  4.11

PubMed score by year
PubTator Score  2.1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer