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Tbio
OVOL1
Putative transcription factor Ovo-like 1

Protein Summary
Description
Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity). This gene encodes a putative zinc finger containing transcription factor that is highly similar to homologous protein in Drosophila and mouse. Based on known functions in these species, this protein is likely involved in hair formation and spermatogenesis in human as well. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335987
  • ENSP00000337862
  • ENSG00000172818

Symbol
  • HOVO1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.98
molecular function
0.84
biological process
0.77
PubMedID
0.77
tissue sample
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.05   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 219   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.05   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 219   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
SUFU
Tbio
Novelty:  0.00475249
p_int:  0.969697469
p_ni:  0.030302523
p_wrong:  9e-9
Score:  0.303
Data Source:  BioPlex,STRINGDB
FLG
Tbio
Novelty:  0.00072986
Score:  0.685
Data Source:  STRINGDB
ACTL9
Tdark
Novelty:  0.33211557
Score:  0.679
Data Source:  STRINGDB
IRF6
Tbio
Family:  TF
Novelty:  0.00209286
Score:  0.655
Data Source:  STRINGDB
LOR
Tbio
Novelty:  0.0033781
Score:  0.642
Data Source:  STRINGDB
GRHL3
Tbio
Family:  TF
Novelty:  0.01447204
Score:  0.621
Data Source:  STRINGDB
RTEL1
Tbio
Family:  Enzyme
Novelty:  0.00761538
Score:  0.585
Data Source:  STRINGDB
ESRP1
Tbio
Novelty:  0.02035464
Score:  0.581
Data Source:  STRINGDB
SIPA1
Tbio
Novelty:  0.03916566
Score:  0.578
Data Source:  STRINGDB
MYC
Tchem
Family:  TF
Novelty:  0.00005734
Score:  0.571
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (16)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (59)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
4
6
7
98.5
glomerular filtration rate
8
7
10
9.3
97.4
sex hormone-binding globulin measurement
6
2
9
92
creatinine measurement
4
4
5
91.4
6
3
0
1.1
84
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
7
98.5
glomerular filtration rate
10
9.3
97.4
sex hormone-binding globulin measurement
9
92
creatinine measurement
5
91.4
0
1.1
84
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ovo like transcriptional repressor 1
VGNC:6698
451332
Macaque
ovo like transcriptional repressor 1
715797
Mouse
MGI:1330290
18426
Rat
RGD:1306956
309164
Dog
ovo like transcriptional repressor 1
VGNC:44196
483727
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ovo like transcriptional repressor 1
Macaque
ovo like transcriptional repressor 1
Mouse
Rat
Dog
ovo like transcriptional repressor 1
Publication Statistics
PubMed Score 24.05
PubMed score by year
PubTator Score 12.79
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title