Tbio GOSR2 Golgi SNAP receptor complex member 2

Protein Summary

Description

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. [provided by RefSeq, Mar 2016]

Uniprot Accession IDs

• O14653
• D3DXJ5
• D3DXJ6
• Q8N4B8
• Q96DA5
• Q9BZZ4

Gene Name

• GOSR2

Ensembl ID

• ENST00000225567
• ENSP00000225567
• ENSG00000108433
• ENST00000640051
• ENSP00000492751
• ENST00000640621
• ENSP00000492830

Symbol

• GS27
• Bos1
• EPM6
• GS27

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.98
transcription factor perturbation	0.91
interacting protein	0.85
disease perturbation	0.83
transcription factor binding site profile	0.81

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Snare Protein / Golgi Snap Receptor Complex Member 2

DTO Classes

Protein / Transporter / Snare Protein / Golgi Snap Receptor Complex Member 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.79   (req: < 5)

Gene RIFs: 20   (req: <= 3)

Antibodies: 133   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.79   (req: >= 5)

Gene RIFs: 20   (req: > 3)

Antibodies: 133   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0