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Tdark
ZNF195
Zinc finger protein 195

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000005082
  • ENSP00000005082
  • ENSG00000005801
  • ENST00000343338
  • ENSP00000344483
  • ENST00000354599
  • ENSP00000346613
  • ENST00000399602
  • ENSP00000382511
  • ENST00000429541
  • ENSP00000387998
  • ENST00000438262
  • ENSP00000414353
  • ENST00000526601
  • ENSP00000435828
  • ENST00000528218
  • ENSP00000436384
  • ENST00000618467
  • ENSP00000482411

Symbol
  • ZNFP104
  • HRF1
  • ZNFP104
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
cell type or tissue
0.59
protein domain
0.58
histone modification site profile
0.57
disease perturbation
0.56


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.07   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 126   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.07   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 126   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 195
VGNC:12795
450964
Macaque
zinc finger protein 195
706915
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 195
Macaque
zinc finger protein 195
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O14628-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (21)
1 – 10 of 21
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.999979523
p_ni:  0.000020477
Score:  0.929
Data Source:  BioPlex,STRINGDB
RFPL4B
Tdark
Novelty:  2.42779597
p_int:  0.999672588
p_ni:  0.000327388
p_wrong:  2.4e-8
Score:  0.227
Data Source:  BioPlex,STRINGDB
L3MBTL1
Tchem
Family:  TF; Epigenetic
Novelty:  0.02321712
p_int:  0.999178558
p_ni:  0.000821383
p_wrong:  5.9e-8
Score:  0.219
Data Source:  BioPlex,STRINGDB
THSD4
Tbio
Novelty:  0.12898073
p_int:  0.997219492
p_ni:  0.001704095
p_wrong:  0.001076413
Score:  0.169
Data Source:  BioPlex,STRINGDB
C6orf141
Tdark
Novelty:  1.46022784
p_int:  0.996806155
p_ni:  0.003189236
p_wrong:  0.000004609
Data Source:  BioPlex
IL13RA2
Tbio
Novelty:  0.03465642
p_int:  0.996537693
p_ni:  0.00321101
p_wrong:  0.000251298
Data Source:  BioPlex
P4HA2
Tbio
Family:  Enzyme
Novelty:  0.02097718
p_int:  0.992997296
p_ni:  0.00690358
p_wrong:  0.000099123
Data Source:  BioPlex
PIAS4
Tbio
Family:  TF
Novelty:  0.01388547
p_int:  0.972856133
p_ni:  0.025523045
p_wrong:  0.001620822
Data Source:  BioPlex
DRC3
Tdark
Novelty:  0.99283468
p_int:  0.823453483
p_ni:  0.00244074
p_wrong:  0.174105776
Data Source:  BioPlex
F7
Tchem
Family:  Enzyme
Novelty:  0.0002521
Score:  0.8
Data Source:  STRINGDB
Publication Statistics
PubMed Score  4.07

PubMed score by year
PubTator Score  9.8

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer