Tbio CCS Copper chaperone for superoxide dismutase

Protein Summary

Description

Delivers copper to copper zinc superoxide dismutase (SOD1). Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O14618
• Q2M366
• Q8NEV0

Gene Name

• CCS

Ensembl ID

• ENST00000533244
• ENSP00000436318
• ENSG00000173992

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.88
histone modification site profile	0.85
tissue sample	0.64
cell line	0.61
cell type or tissue	0.57

Protein Classes

PANTHER Classes

Protein / Oxidoreductase / Copper Chaperone For Superoxide Dismutase

DTO Classes

Protein / Enzyme / Oxidoreductase / Copper Chaperone For Superoxide Dismutase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.84   (req: < 5)

Gene RIFs: 30   (req: <= 3)

Antibodies: 337   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 70.84   (req: >= 5)

Gene RIFs: 30   (req: > 3)

Antibodies: 337   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0