NCAN
Neurocan core protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
virus perturbation | 0.76 | ||
cell type or tissue | 0.62 | ||
microRNA | 0.6 | ||
biological process | 0.57 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | A tetrasaccharide linker sequence is required for GAG synthesis | ||||
Reactome | Axon guidance | ||||
Reactome | CS/DS degradation | ||||
Reactome | Chondroitin sulfate biosynthesis | ||||
Reactome | Chondroitin sulfate/dermatan sulfate metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
A tetrasaccharide linker sequence is required for GAG synthesis | ||||
Axon guidance | ||||
CS/DS degradation | ||||
Chondroitin sulfate biosynthesis | ||||
Chondroitin sulfate/dermatan sulfate metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 14 | 11 | 20 | 3.8 | 99.8 | ||||
triglyceride measurement | 18 | 10 | 28 | 8.2 | 99.6 | ||||
total cholesterol measurement | 9 | 6 | 13 | 4.4 | 99.4 | ||||
apolipoprotein B measurement | 2 | 4 | 4 | 98.5 | |||||
serum alanine aminotransferase measurement | 3 | 4 | 4 | 17.9 | 98.4 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 20 | 3.8 | 99.8 | ||||
triglyceride measurement | 28 | 8.2 | 99.6 | ||||
total cholesterol measurement | 13 | 4.4 | 99.4 | ||||
apolipoprotein B measurement | 4 | 98.5 | |||||
serum alanine aminotransferase measurement | 4 | 17.9 | 98.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | neurocan | VGNC:2306 | 468775 | |||||
Mouse | MGI:104694 | 13004 | ||||||
Rat | RGD:619941 | 58982 | ||||||
Dog | neurocan | VGNC:43638 | 484808 | |||||
Horse | neurocan [Source:HGNC Symbol;Acc:HGNC:2465] | |||||||
PMID | Year | Title |
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