DPYSL4
Dihydropyrimidinase-related protein 4
Protein Summary
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
- ENST00000338492
- ENSP00000339850
- ENSG00000151640
- CRMP3
- ULIP4
- CRMP3
- DRP-4
- ULIP4
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.8 | ||
transcription factor perturbation | 0.8 | ||
disease perturbation | 0.68 | ||
transcription factor | 0.57 | ||
small molecule perturbation | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.62 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 196 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.62 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 196 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0