CUX2
Homeobox protein cut-like 2
Protein Summary
May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner (By similarity). This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. [provided by RefSeq, Jan 2013]
- ENST00000261726
- ENSP00000261726
- ENSG00000111249
- CUTL2
- KIAA0293
- CDP2
- CUTL2
- EIEE67
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.87 | ||
biological process | 0.86 | ||
protein domain | 0.73 | ||
cellular component | 0.61 | ||
trait | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 75.32 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 69 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 75.32 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 69 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 15
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0