SDHD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.99 | ||
histone modification site profile | 0.93 | ||
kinase perturbation | 0.93 | ||
cellular component | 0.9 | ||
phenotype | 0.81 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Citric acid cycle (TCA cycle) | ||||
Reactome | Metabolism | ||||
Reactome | Pyruvate metabolism and Citric Acid (TCA) cycle | ||||
Reactome | Respiratory electron transport | ||||
Reactome | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Citric acid cycle (TCA cycle) | ||||
Metabolism | ||||
Pyruvate metabolism and Citric Acid (TCA) cycle | ||||
Respiratory electron transport | ||||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
interleukin 18 measurement | 3 | 3 | 3 | 98.1 | |||||
waist-hip ratio | 2 | 2 | 2 | 83 | |||||
blood protein measurement | 1 | 1 | 1 | 80.8 | |||||
interleukin 1 receptor antagonist measurement | 1 | 1 | 1 | 80.5 | |||||
interleukin-1 beta measurement | 1 | 1 | 1 | 80.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
interleukin 18 measurement | 3 | 98.1 | |||||
waist-hip ratio | 2 | 83 | |||||
blood protein measurement | 1 | 80.8 | |||||
interleukin 1 receptor antagonist measurement | 1 | 80.5 | |||||
interleukin-1 beta measurement | 1 | 80.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | succinate dehydrogenase complex subunit D | 106992278 | ||||||
Mouse | MGI:1914175 | 66925 | ||||||
Rat | RGD:735231 | 363061 | ||||||
Cow | succinate dehydrogenase complex subunit D | 281481 | ||||||
Pig | succinate dehydrogenase complex subunit D | 100048954 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | succinate dehydrogenase complex subunit D | |||||
Mouse | ||||||
Rat | ||||||
Cow | succinate dehydrogenase complex subunit D | |||||
Pig | succinate dehydrogenase complex subunit D | |||||
PMID | Year | Title |
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