Tbio DLGAP1 Disks large-associated protein 1

Protein Summary

Description

Part of the postsynaptic scaffold in neuronal cells.

Uniprot Accession IDs

• O14490
• A8MWN8
• B2RMU8
• B7WPA1
• B7Z2H2
• B7Z2I2
• B7Z9Y4
• O14489
• P78335
• DAP-1

Gene Name

• DLGAP1

Ensembl ID

• ENST00000315677
• ENSP00000316377
• ENSG00000170579
• ENST00000400145
• ENSP00000383010
• ENST00000400147
• ENSP00000383011
• ENST00000400155
• ENSP00000383019
• ENST00000534970
• ENSP00000437817
• ENST00000539435
• ENSP00000446312
• ENST00000581527
• ENSP00000463864
• ENST00000581699
• ENSP00000462848

Symbol

• DAP1
• GKAP
• DAP1
• GKAP
• DAP-1
• SAPAP1
• DLGAP1A
• DLGAP1B
• DAP-1-BETA
• DAP-1-ALPHA

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	1
hub protein	0.98
microRNA	0.89
transcription factor	0.75
phenotype	0.72

Protein Classes

PANTHER Classes

Protein / Transmembrane Receptor Regulatory/adaptor Protein / Disks Large-associated Protein 1

DTO Classes

Protein / Receptor / Disks Large-associated Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.79   (req: < 5)

Gene RIFs: 21   (req: <= 3)

Antibodies: 228   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.79   (req: >= 5)

Gene RIFs: 21   (req: > 3)

Antibodies: 228   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0