Protein Summary
Anchoring filament protein which is a component of the basement membrane zone. The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme. [provided by RefSeq, Jul 2008]
- ENST00000391967
- ENSP00000375829
- ENSG00000159166
- LAD
- LadA
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.9 | ||
interacting protein | 0.85 | ||
gene perturbation | 0.76 | ||
transcription factor perturbation | 0.61 | ||
kinase perturbation | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.07 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 142 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.07 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 142 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0