Tbio ZNF593 Zinc finger protein 593

Protein Summary

Description

Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.

Uniprot Accession IDs

• O00488
• B2R4S0
• Q5T2H7

Gene Name

• ZNF593

Ensembl ID

• ENST00000374266
• ENSP00000363384
• ENSG00000142684

Symbol

• ZT86
• ZT86

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.85
transcription factor	0.8
transcription factor binding site profile	0.76
cell type or tissue	0.67
disease perturbation	0.62

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Zinc Finger Protein 593

DTO Classes

Protein / Nucleic Acid Binding / Zinc Finger Protein 593

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.31   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.31   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0