POLRMT
DNA-directed RNA polymerase, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.95 | ||
histone modification site profile | 0.79 | ||
disease perturbation | 0.68 | ||
transcription factor perturbation | 0.68 | ||
tissue sample | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Mitochondrial biogenesis | ||||
Reactome | Mitochondrial transcription initiation | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Reactome | Transcription from mitochondrial promoters | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Mitochondrial biogenesis | ||||
Mitochondrial transcription initiation | ||||
Organelle biogenesis and maintenance | ||||
Transcription from mitochondrial promoters | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 2 | 3 | 41.9 | |||||
worry measurement | 1 | 1 | 1 | 33.1 | |||||
cognitive function measurement | 2 | 1 | 2 | 31.4 | |||||
mathematical ability | 1 | 1 | 1 | 21.5 | |||||
pulse pressure measurement | 1 | 1 | 1 | 14 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 41.9 | |||||
worry measurement | 1 | 33.1 | |||||
cognitive function measurement | 2 | 31.4 | |||||
mathematical ability | 1 | 21.5 | |||||
pulse pressure measurement | 1 | 14 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:1915843 | 216151 | ||||||
Rat | RGD:1304599 | 299604 | ||||||
Cow | RNA polymerase mitochondrial | VGNC:33154 | 504757 | |||||
Opossum | RNA polymerase mitochondrial | 100024662 | ||||||
Chicken | RNA polymerase mitochondrial | CGNC:944 | 420084 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Cow | RNA polymerase mitochondrial | |||||
Opossum | RNA polymerase mitochondrial | |||||
Chicken | RNA polymerase mitochondrial | |||||
PMID | Year | Title |
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